急性缺血性腦血管病合并腦微出血的臨床分析

摘要： 目的探討不同類型的急性缺血性腦血管病合并腦微出血(cerebral microbleeds,CMB)的陽性檢出率及其臨床意義。方法將急性缺血性腦血管病患者204例以及同期健康體檢者35例均行常規(guī)磁共振成像(magnetic resonance imaging,MRI)和磁共振梯度回波T2加權(quán)成像(T2~*-weighted gradient-echo magnetic resonanceimaging,GRE-T2~*WI)檢查。結(jié)果動脈粥樣硬化血栓性腦梗死組、心源性腦栓塞組及腔隙性腦梗死組患者CMB陽性檢出率均高于正常對照組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05);短暫性缺血發(fā)作組與正常對照組的陽性檢出率差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。結(jié)論 GRE-T2~*WI對CMB敏感性較高,對急性缺血性腦血管病患者的治療和預(yù)后具有指導(dǎo)意義。
Objective To investigate the positive detection rate and clinical significance of different types of acute ischemic cerebrovascular disease combined with cerebral microbleeds(CMB). Methods A total of 204 patients with acute ischemic cerebrovascular disease and 35 healthy control underwent examinations of magnetic resonance imaging(MRI) and T2~* - weighted gradient - echo magnetic resonance imaging(GRE - T2~* WI).Results The CMB positive detection rate of the atherosclerosis thrombosis cerebral infarction group,the cardiogenic cerebral embolism group and the lacunar cerebral infarction group were higher than the control group,and there were statistical differences between these groups(P<0.05).There was no significant difference between transient ischemic group (TIA) and control group in detection rate(P>0.05 ).Conclusion GRE - T2~* WI has higher sensitivity to CMB,and it has a guiding role in the the therapy and the prognosis of patients with acute ischemic cerebrovascular disease.