皮膚再生復(fù)原技術(shù)治療面部燒傷的回顧分析

摘要： 目的:回顧分析皮膚再生復(fù)原技術(shù)治療面部燒傷的臨床應(yīng)用效果,總結(jié)人體面部燒傷創(chuàng)面的再生復(fù)原規(guī)律和實(shí)施規(guī)范。方法:根據(jù)徐榮祥教授人體再生復(fù)原科學(xué)理論和方法,通過臨床研究課題組對規(guī)范應(yīng)用"皮膚器官原位再生復(fù)原技術(shù)"治療的968例樣本資料進(jìn)行統(tǒng)計學(xué)分析,論證皮膚原位再生復(fù)原療法的理論基礎(chǔ)和臨床實(shí)用價值。結(jié)果:淺Ⅱ度創(chuàng)面5天～7天無瘢痕再生復(fù)原愈合,實(shí)現(xiàn)率為100%;深Ⅱ度創(chuàng)面16天～20天無瘢痕再生愈合,實(shí)現(xiàn)率為99.98%;淺Ⅲ度創(chuàng)面26天～32天無瘢痕再生愈合,實(shí)現(xiàn)率為97.90%;深Ⅲ度創(chuàng)面36天～42天無瘢痕或淺瘢痕再生愈合,實(shí)現(xiàn)率為81.87%,配合自體皮移植可達(dá)100%再生愈合,無明顯毀容。傷后及時治療與否、燒傷嚴(yán)重程度、年齡及患者原有健康狀況對療效均有影響,得到BRT治療越早、燒傷嚴(yán)重程度越輕、年齡越小和越健康者效果越好。結(jié)論:潛能再生細(xì)胞理論和原位干細(xì)胞培植再生修復(fù)技術(shù)是燒傷皮膚再生復(fù)原技術(shù)的理論基礎(chǔ)和實(shí)用醫(yī)療技術(shù)。燒傷創(chuàng)面的生理性原位皮膚再生修復(fù)需要具備三個條件:一是燒傷創(chuàng)面生理濕潤環(huán)境的形成;二是原位培養(yǎng)角蛋白K-19型干細(xì)胞的再生物質(zhì)和組織學(xué)基礎(chǔ);三是規(guī)范的皮膚再生醫(yī)療技術(shù)是創(chuàng)面生理性再生愈合的保證。皮膚再生復(fù)原療法對燒傷創(chuàng)面愈合有明顯促進(jìn)作用,能使深度燒傷創(chuàng)面達(dá)到生理性再生復(fù)原愈合,認(rèn)為皮膚原位再生復(fù)原技術(shù)是面部燒傷尤其是深Ⅱ度和淺Ⅲ度燒傷的首選方法。
Objective:To retrospectively review treating facial burns with Skin Regenerative Restoration Therapy in situ so as to summarize regenerative restoration laws and implementation norm of treating facial burns with the Therapy. Method:On the basis of statistical analysis large sample data of 968 cases treated with the Therapy,theoretical basis and clinical value of the Therapy were discussed according to the theory and method of Professor Xu's Human Regeneration and Restoration Science.Results:The results of this analysis demonstrated that the Skin Regenerative Restoration Therapy in situ,which targets at skin regeneration in situ by PRCS,was fully different from conventional west - medicine technique, the result of which was healing with scar formation.Of reviewed 968 cases,the regenerative healing rate was 100%for superficialⅡdegree burn wounds with healing time of 5 -7 days;for the deepⅡdegree burn wounds,it was 99.98%with healing time of 16 -20 days,while the healing rates for superficialⅢdegree burn and deepⅢdegree burn were 97.90% with 26 -32 days and 81.87%with 36 -42 days healing time respectively.If micro - skin grafting or mesh skin grafting were combined with the Therapy,regenerative healing rate even reached to 100%for both superficial and deepⅢburns and no obvious dysfunction observed.Conclusion:Theory of PRCS is a theoretic basis of Burn Skin Regenerative Therapy and Stem cell regenerative restoration technique is a practical technique of physiologically regenerative restoration of burn skin.To realize the restoration,it needs three conditions:first,a moist physiological environment at burn wound site;second, regeneration material and histological basis of cultivating keratin 19 - type of stem cell in situ;last,standardized operation of Skin Regenerative Restoration Therapy in situ provides an assurance of physiological regenerative healing of burn wounds.